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KMID : 0363320070280020217
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Journal of Korean Oriental Internal Medicine
2007 Volume.28 No. 2 p.217 ~ p.229
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Experimental Studies on the Anti-cathartic Effects of Bojangjisa-tang
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Lee Seon-Young
Ryu Bong-Ha
Park Jae-Woo
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Abstract
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Objectives : The aim of this experimental study was to investigate the effects of Bojangjisa-tang on anticatharsis by using mice and Guinea pigs.
Methods : We observed the actions on gastrointestinal smooth muscles, on the transportability of small and large intestines and on diarrhea induced by castor oil, philocarpine, and barium chloride.
Results : Bojangjisa-tang showed alleviation of the contraction of gastrointestinal smooth muscles induced by acetylcholine chloride and barium chloride. The transportability of the large intestine was constrained by Bojangjisa-tang, which also showed substantial anti-cathartic effects on diarrhea induced by castor oil, philocarpine and barium chloride.
Conclusion : These results demostrate that Bojangjisa-tang has advantageous effects on drug-induced diarrhea and will contribute to the development of diarrhea treatment through further related studies.
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KEYWORD
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Bojangjisa-tang, Anticathartic action
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